CME/CE Information

Activity Title Evaluating the Efficacy of Disease Modifying Therapies for Relapsing-Remitting Multiple Sclerosis
Topic Multiple Sclerosis
Accreditation Type AMA PRA Category 1 Credits™/ANCC Contact Hours
Release Date October 2015
Expiration Date October 31, 2016
Estimated Time to Complete Activity 15 minutes


Upon completion of the activity, participants should be able to:

  • Differentiate between key characteristics of newer (non-platform) MS therapies that can be considered when starting or switching treatment
  • Evaluate criteria that can support the decision to initiate or switch treatment


Robert A. Bermel, MD
Medical Director, Mellen Center for Multiple Sclerosis
Assistant Professor of Neurology
Cleveland Clinic
Cleveland, Ohio


  1. There are no fees for participating in and receiving credit for this activity.
  2. Review the activity objectives and CME/CNE information.
  3. Complete the CME/CNE activity.
  4. Complete the online posttest. A score of at least 75% is required to successfully complete this activity. The participant may take the test until successfully passed.
  5. Complete the CME/CNE evaluation/attestation form, which provides each participant with the opportunity to comment on how participating in the activity will affect their professional practice; the quality of the instructional process; the perception of enhanced professional effectiveness; the perception of commercial bias; and his/her views on future educational needs.
  6. Credit documentation/reporting: your CME/CNE certificate will be available for download.


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This activity is provided by Consortium of Multiple Sclerosis Centers in collaboration with Nurse Practitioner Alternatives and The France Foundation.


This activity is intended for neurologists, nurses, nurse practitioners, physician assistants, rehabilitation professionals, case managers, mental health professionals, social workers and others involved in the management of patients with MS.


The number of FDA-approved disease modifying therapies (DMTs) for patients with MS has grown considerably over the last 2 decades. These agents vary by mechanism of action, mode of administration, dosing frequency, side effect profiles and monitoring recommendations. The increasing range of treatment options allows for individualized treatment selection for this patient population; however consensus and guidelines regarding the criteria and timing for switching DMTs are limited. It is critical that clinicians managing patients with MS are familiar with current evidence to support optimal treatment decisions over the disease course.


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of the Consortium of Multiple Sclerosis Centers (CMSC), Nurse Practitioner Alternatives (NPA), and The France Foundation.

The Consortium of Multiple Sclerosis Centers (CMSC) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CMSC designates this enduring activity for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioner Alternatives is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

This activity is awarded 0.25 contact hour(s) of continuing nursing education for RNs and APRNs. Laurie Scudder, DNP, NP, has served as Nurse Planner for this activity. She has declared that she has no relevant financial relationships to disclose.


In accordance with the ACCME Standards for Commercial Support of CME and ANCC accreditation standards, the Consortium of Multiple Sclerosis Centers, Nurse Practitioner Alternatives, and The France Foundation have implemented mechanisms, prior to the planning and implementation of this CME/CNE activity, to identify and resolve conflicts of interest for all individuals in a position to control content of this CME/CNE activity.


It is the policy of CMSC, NPA, and The France Foundation to ensure balance, independence, objectivity, and scientific rigor in all its sponsored educational activities. All faculty, activity planners, content reviewers, and staff participating in this activity have disclosed to the participants any significant financial interest or other relationship with manufacturer(s) of any commercial product(s)/device(s) and/or provider(s) of commercial services included in this educational activity. The intent of this disclosure is not to prevent a person with a relevant financial or other relationship from participating in the activity, but rather to provide participants with information on which they can base their own judgments. CMSC, NPA, and The France Foundation have identified and resolved any and all conflicts of interest prior to the release of this activity.

Activity Staff Disclosures

June Halper has disclosed that she serves as a Consultant for non-clinical subject matter to Biogen Idec. All other planners, reviewers, staff, or other members of the Continuing Professional Education Committee at the Consortium of Multiple Sclerosis Centers who control content have no relevant financial relationships to disclose.

The planners, reviewers, and staff at Nurse Practitioner Alternatives who control content have no relevant financial relationships to disclose.

The planners, reviewers, editors, staff, CME committee, or other members at The France Foundation who control content have no relevant financial relationships to disclose.

Faculty Disclosure

The following faculty report that they have relevant financial relationships to disclose:

  • Robert A. Bermel, MD, has served as a consultant for Biogen, Novartis, Genzyme and Genentech and received licensing fees from Biogen.

Disclosure of Unlabeled Use

CMSC, NPA, and TFF require CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental, and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of US Food and Drug Administration approved labeling. This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. CMSC, NPA, and TFF do not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.


This activity is supported by educational grants from Biogen and Mallinckrodt Pharmaceuticals.


CMSC, NPA, and TFF present this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. CMSC, NPA, and TFF assume no liability for the information herein.


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If you have questions about this CME/CNE activity, please contact The France Foundation at 860-434-1650 or