Strategies to Improve the Care of MS in Women

Contraceptive Techniques

Joy A. Derwenskus, DO
Northwestern University

Susan M. Rubin, MD
NorthShore University HealthSystem
University of Chicago Pritzker School of Medicine


DMTs and Pregnancy
Coyle PK. Multiple sclerosis and pregnancy prescriptions. Expert Opin Drug Saf. 2014;13(12):1565-1568.

Oral Contraception and MS Risk
Alonso A, Jick SS, Olek MJ, Ascherio A, Jick H, Hernán MA. Recent use of oral contraceptives and the risk of multiple sclerosis. Arch Neurol. 2005;62(9):1362-1365.

Hernán MA, Hohol MJ, Olek MJ, Spiegelman D, Ascherio A. Oral contraceptives and the incidence of multiple sclerosis. Neurology. 2000;55(6):848-854.

Villard-Mackintosh L, Vessey MP. Oral contraceptives and reproductive factors in multiple sclerosis incidence. Contraception. 1993;47(2):161-168.

Thorogood M, Hannaford PC. The influence of oral contraceptives on the risk of multiple sclerosis. Br J Obstet Gynaecol. 1998;105(12):1296-1299.

Holmqvist P, Hammar M, Landtblom AM, Brynhildsen J. Age at onset of multiple sclerosis is correlated to use of combined oral contraceptives and childbirth before diagnosis. Fertil Steril. 2010;94(7):2835-2837.

Oral Contraceptive Progestin Content and MS/CIS
Langer-Gould AM, Hellwig K, Chen LH, Schroeder C, Stancyzk F. Progestin content of oral contraceptives and the risk of multiple sclerosis. Mult Scler. 2014; 20: (S1) 285–496. Abstract P856.

Oral Contraception and MS Course
D'hooghe MB, Haentjens P, Nagels G, D'Hooghe T, De Keyser J. Menarche, oral contraceptives, pregnancy and progression of disability in relapsing onset and progressive onset multiple sclerosis. J Neurol. 2012;259(5):855-861.

Sena A, Couderc R, Vasconcelos JC, Ferret-Sena V, Pedrosa R. Oral contraceptive use and clinical outcomes in patients with multiple sclerosis. J Neurol Sci. 2012;317(1-2):47-51.

Gava G, Bartolomei I, Costantino A, et al. Long-term influence of combined oral contraceptive use on the clinical course of relapsing-remitting multiple sclerosis. Fertil Steril. 2014;102(1):116-122.